反応 #1528403

反応方程式

2-benzyloxy-4,6-dimethylpyridin-3-yl 3-fluoro-4-methylphenyl methanol

→

title compound

収率 80.8%

3-(3-Fluoro-4-methylbenzyl)-4,6-dimethyl-1H-pyridin-2-one

収率 80.8%

溶媒

ethanol

反応条件

後処理

1. 1
   その他After the insoluble material was removed by filtration
2. 2
   その他the solvent of the filtrate was removed

実験手順

To a solution of 2-benzyloxy-4,6-dimethylpyridin-3-yl 3-fluoro-4-methylphenyl methanol (0.39 g) in ethanol (10 mL) was added a catalytic amount of palladium carbon powder, and the mixture was stirred at room temperature under a hydrogen atmosphere overnight. After the insoluble material was removed by filtration, the solvent of the filtrate was removed to give the title compound (0.22 g).

出典