反応 #1519128

ord-24ba5225d00742d5ad6fed9d1a8c1c78

反応方程式

c1cc(C2CCNC2)ccn1
4-pyrrolidin-3-yl-pyridine
CCCCC(C(=O)O)C1OC(C)(C)OC1=O
2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid
CCCC[C@@H](C(=O)N1CCC(c2ccncc2)C1)[C@H](O)C(=O)O
title compound
CCCC[C@@H](C(=O)N1CCC(c2ccncc2)C1)[C@H](O)C(=O)O
(S)-hydroxy-3 (R)-[3 (R/S)-pyridin-4-yl-pyrrolidine-1-carbonyl)-heptanoic acid

反応条件

詳細条件
See reaction.notes.procedure_details.

実験手順

The title compound is prepared from 2-(2,2-dimethyl-4-oxo-1,3-dioxolan-5-yl)hexanoic acid B-5 and commercially available 4-pyrrolidin-3-yl-pyridine A-5 according to General Procedure B.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US07612059B2uspto-grants-2009_11