反応 #1519116

反応方程式

(2S,3R)-3-(2-butenyl)-2-hydroxysuccinic dimethyl ester

→

(2S,3R)-3-(n-butyl)-2-hydroxysuccinic dimethyl ester

溶媒

EtOAc

反応条件

後処理

1. 1
   ろ過The suspension is filtered through Celite
2. 2
   洗浄washed with EtOAc (3×)
3. 3
   濃縮concentrated in vacuo

実験手順

To (2S,3R)-3-(2-butenyl)-2-hydroxysuccinic dimethyl ester B-2 (2.5 g) in EtOAc (50 mL) is added 10% Pd/C (0.25 g) and the reaction stirred under a hydrogen atmosphere for 20 hours. The suspension is filtered through Celite, washed with EtOAc (3×) and then concentrated in vacuo to afford (2S,3R)-3-(n-butyl)-2-hydroxysuccinic dimethyl ester B-3.

出典