反応 #1519094

反応方程式

4-Benzyloxybenzyl chloride

triphenyl phosphine

ether

→

4-benzyloxybenzyltriphenyl phosphonium chloride

溶媒

toluene

反応条件

後処理

1. 1
   ろ過The precipitated phosphonium salt was collected by filtration
2. 2
   洗浄rinsed with ether and air
3. 3
   その他dried

実験手順

4-Benzyloxybenzyl chloride (1 g, 0.0043 moles) and triphenyl phosphine (1.127 g, 1 equivalent) in anhydrous toluene (20 mL) were refluxed under nitrogen for ˜8-10 hours. A white precipitate appeared in the reaction mixture. The reaction mixture was then cooled to room temperature and ether (100 mL) was added. The precipitated phosphonium salt was collected by filtration, rinsed with ether and air dried. Yield=0.55 g (25%). MALDI-TOF MS 459.51 obs. (459.54 calc.).

出典