反応 #1512

反応方程式

6-decyloxynaphthalene-2-carboxylic acid

hydrobromic acid

→

1,2,3,4-tetrahydro-6-hydroxynaphthalene-2-carboxylic acid

収率 100.0%

溶媒

acetic acid

反応条件

後処理

1. 1
   温度was heated
2. 2
   workup.ADDITIONTo the reaction mixture was added
3. 3
   workup.DISTILLATIONdistilled water
4. 4
   濃縮the resulting mixture was concentrated under reduced pressure

実験手順

16.6 g (50 mmol) of the 6-decyloxynaphthalene-2-carboxylic acid obtained in the first stage was heated under reflux at 130° C. for 7 hours in the presence of 250 cc of acetic acid and 86.5 g (0.5 mol) of 47% hydrobromic acid. To the reaction mixture was added distilled water, and then the resulting mixture was concentrated under reduced pressure to obtain 10.60 g (50 mmol) of 1,2,3,4-tetrahydro-6-hydroxynaphthalene-2-carboxylic acid.

出典