反応 #1509611

反応方程式

3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene

water acetonitrile

ethyl bromoglutarate

→

2-(3,6,9,15-Tetraazabicyclo[9.3.1]pentadeca-1(15),11,13-trien-3-yl)pentanedioic acid diethyl ester

反応条件

実験手順

10 mg of 3,6,9,15-tetraazabicyclo[9.3.1]pentadeca-1(14),11(15),12-triene (48.5 μmol) are dissolved in a water-acetonitrile mixture (170 μl of acetonitrile and 7 μl of water). After the addition of 10 μl of TEA (1.4 eq), the mixture is heated to 50° C. and then 13 mg of ethyl bromoglutarate (1 eq) are added. The medium is stirred at 50° C. for 18 h.

出典