反応 #1501983

反応方程式

3-nitrocinnamic acid methyl ester

charcoal

hydrogen

→

3-aminocinnamic acid methyl ester

収率 100.6%

溶媒

methanol

反応条件

後処理

1. 1
   その他evaporated

実験手順

50 g of 3-nitrocinnamic acid methyl ester in 350 ml of methanol are hydrogenated in the presence of 1.5 g of the platinum sulphide catalyst described in Example 6 (5% strength on active charcoal) for 2 hours at 70° C and one half hour at 80° C under 130 bars hydrogen pressure in a stirred autoclave of 700 ml capacity. The pressure drop has ceased after 2 hours. The solution is freed from the catalyst and evaporated. 43 g of crystalline 3-aminocinnamic acid methyl ester of melting point 75° C are obtained.

出典