反応 #1470425

反応方程式

1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine

diethanolamine

→

title compound

収率 29.9%

1-Oxyl-2,2,6,6-tetramethyl-4-{2-hydroxy-3-[di(2-hydroxyethyl)amino]propoxy}piperidine

収率 29.9%

溶媒

water

反応条件

後処理

1. 1
   抽出The solution is then extracted with methylene chloride
2. 2
   抽出The methylene chloride extract
3. 3
   乾燥is dried over anhydrous magnesium sulfate
4. 4
   ろ過filter
5. 5
   濃縮concentrated
6. 6
   その他The crude reaction product
7. 7
   その他is purified by column chromatography

実験手順

A solution of 2.28 g (0.01 mol) of 1-oxyl-2,2,6,6-tetramethyl-4-glycidyloxypiperidine and 1.05 g (0.01 mol) of diethanolamine in 25 mL of water is stirred at ambient temperature for 16 hours. The solution is then extracted with methylene chloride. The methylene chloride extract is dried over anhydrous magnesium sulfate, filter and concentrated. The crude reaction product is purified by column chromatography to afford 1.0 g of the title compound as a red oil.

出典