反応 #1447111

反応方程式

Et3N

1-naphthol

phosphorus oxychloride

→

title compound

1-Naphthyl dichlorophosphate

溶媒

Et2O

反応条件

後処理

1. 1
   workup.WAITthe resulting solution was left
2. 2
   温度to warm to RT overnight
3. 3
   ろ過The white slurry was filtered under an inert atmosphere
4. 4
   その他all volatiles were removed

実験手順

To 1-naphthol in Et2O (0.23 M) was added phosphorus oxychloride (1.0 eq.) and the solution was cooled to −78° C. Neat Et3N (1.0 eq) was added and the resulting solution was left to warm to RT overnight. The white slurry was filtered under an inert atmosphere and all volatiles were removed to yield the title compound as a colorless liquid that was used without further purification in the next step. 31P NMR (400 MHz, CDCl3): δ 3.93 ppm.

出典