反応 #1435711

反応方程式

1-(5-cyano-2-thienyl)-4,4,5,5,5-pentafluoro-1,3-pentanedione

sulfuric acid

acetic acid

→

1-(5-Carboxy-2-thienyl)-4,4,5,5,5-pentafluoro-1,3-pentanedione

溶媒

water

反応条件

後処理

1. 1
   温度was refluxed for 2 hours
2. 2
   その他The precipitation
3. 3
   ろ過was filtered
4. 4
   洗浄washed with water

実験手順

A mixture of 1-(5-cyano-2-thienyl)-4,4,5,5,5-pentafluoro-1,3-pentanedione (0.78 g), sulfuric acid (9 ml) and acetic acid (10 ml) was refluxed for 2 hours. The cooled mixture was poured into 100 ml of water. The precipitation was filtered and washed with water. 1H NMR (CDCl3): 6.53 (s, 1 H); 7.57 (d, 1 H, J=4.1 Hz); 7.78 (d, 1 H, J=4.1 Hz).

出典