反応 #1435682

反応方程式

HCl

2,4-dinitro-6-methylanisole

ethanol

hydrogen

→

2,4-Diamino-6-methylanisole dihydrochloride

溶媒

water

反応条件

後処理

1. 1
   温度Subsequently, the mixture was cooled
2. 2
   ろ過The catalyst was filtered off
3. 3
   その他the filtrate was evaporated to dryness on a rotary evaporator
4. 4
   抽出The residue was extracted
5. 5
   ろ過filtered off
6. 6
   その他dried overnight under reduced pressure

実験手順

105 g of 2,4-dinitro-6-methylanisole, 1.35 l of ethanol, 150 ml of water and 1 g of Pd/C (5% strength) were initially introduced into the autoclave and hydrogenated at 50° C. with a hydrogen pressure of 50 bar for 12 h. Subsequently, the mixture was cooled and then poured into 1.0 l of semiconcentrated HCl. The catalyst was filtered off, and the filtrate was evaporated to dryness on a rotary evaporator. The residue was extracted by boiling with 2×150 ml of ethanol, filtered off and dried overnight under reduced pressure.

出典