反応 #1375813

反応方程式

methyl 4-tri-n-butylstannylbenzoate

KOH

acetic acid

water

→

title compound

収率 90.3%

4-Tri-n-butylstannylbenzoic acid

収率 90.3%

溶媒

ethanol

反応条件

後処理

1. 1
   温度The resulting solution was refluxed for 2 hours
2. 2
   温度The solution was cooled
3. 3
   抽出The solution was then extracted with diethyl ether (80 ml)
4. 4
   洗浄The ether phase was washed with water (30 ml)
5. 5
   乾燥dried over MgSO4 (5 g)
6. 6
   ろ過filtered
7. 7
   その他evaporated under reduced pressure

実験手順

To a solution of methyl 4-tri-n-butylstannylbenzoate (3.0 g, 7 mmol) in absolute ethanol (60 ml) was added 0.25 g KOH (9 mmol). The resulting solution was refluxed for 2 hours. The solution was cooled and poured into an ice-cold solution of acetic acid (0.64 g, 10.6 mmol) and water (100 ml). The solution was then extracted with diethyl ether (80 ml). The ether phase was washed with water (30 ml), dried over MgSO4 (5 g), filtered and evaporated under reduced pressure to afford 2.6 g (88%) of the title compound. This material was used without further purification.

出典