反応 #1351

反応方程式

ethanolamine

methyl acetoacetate

→

XXIII

収率 91.2%

3-(2-Hydroxyethylamino)-but-2-enoic acid methyl ester

収率 91.2%

反応条件

実験手順

To an ice-cooled sample of ethanolamine (6.1 g) was added methyl acetoacetate (11.6 g) dropwise. Compound (XXIII 14.5 g) was formed within 30 min (U.S. Pat. No. 1102800).

出典