反応 #1350586

反応方程式

methyl 4-methylbenzothiazole-5-carboxylate

phosphoric acid

→

4-Methylbenzothiazole-5-carboxylic Acid

溶媒

potassium hydroxide

反応条件

後処理

1. 1
   温度heated
2. 2
   温度at reflux for 2.5 h
3. 3
   温度After cooling
4. 4
   ろ過The product was filtered off
5. 5
   その他subsequently dried

実験手順

16.6 g of methyl 4-methylbenzothiazole-5-carboxylate (0.08 mol) were dissolved in 280 ml of 5% strength aqueous potassium hydroxide solution and heated at reflux for 2.5 h. After cooling, the mixture was acidified using phosphoric acid. The product was filtered off and subsequently dried.

出典