反応 #1348910

反応方程式

1-benzyloxycarbonyl-4-oxo-1,2,3,4-tetrahydroquinoline

(S,S)-TsDPEN

→

(4S)-1-benzyloxycarbonyl-4-hydroxy-1,2,3,4-tetrahydroquinoline

収率 86.2%

反応条件

実験手順

1-benzyloxycarbonyl-4-oxo-1,2,3,4-tetrahydroquinoline (281 mg), [RuCl2(benzene)]2 (25.0 mg) and (S,S)-TsDPEN (73.3 mg) were treated in the same manner as Example 4 to give 244 mg of (4S)-1-benzyloxycarbonyl-4-hydroxy-1,2,3,4-tetrahydroquinoline (optical purity: 97% ee, yield: 86%).

出典