反応 #1340597

反応方程式

5-aminosalicylic acid

3-(4-nitrophenyl)propyl bromide

→

2-hydroxy-5-[3-(4-nitrophenyl)-n-propylamino]-benzoic acid

収率 50.4%

反応条件

後処理

1. 1
   その他According to the similar procedure to Synthesis Example 1

実験手順

According to the similar procedure to Synthesis Example 1, by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 3-(4-nitrophenyl)propyl bromide (950 mg, 3.92 mmole), 520 mg (50% yield) of 2-hydroxy-5-[3-(4-nitrophenyl)-n-propylamino]-benzoic acid was obtained as a pale yellow solid. Melting point 229-231° C.

出典