反応 #1328403

反応方程式

9-Fluorenone

hydrazine monohydrate

hydrochloric acid

→

9-fluorenone hydrazone

収率 74.0%

溶媒

2-propanol

反応条件

後処理

1. 1
   その他equipped with a reflux condenser and a mechanical stirrer
2. 2
   温度the mixture was refluxed for one hour
3. 3
   ろ過the crude solid product was harvested by filtration
4. 4
   洗浄The solid was washed with isopropanol
5. 5
   その他recrystallized from dioxane

実験手順

9-Fluorenone (200 g, 1.1 mol, from Aldrich, Milwaukee, Wis.) and hydrazine monohydrate (160 ml, 3.3 mol, from Aldrich, Milwaukee, Wis.) were dissolved in 1000 ml of 2-propanol in a 2000 ml 2-neck round bottom flask equipped with a reflux condenser and a mechanical stirrer. Concentrated hydrochloric acid (4 ml) was then added, and the mixture was refluxed for one hour. The mixture was cooled slowly to room temperature, and the crude solid product was harvested by filtration. The solid was washed with isopropanol and then recrystallized from dioxane to obtain 150 g (74% yield) of 9-fluorenone hydrazone.

出典