反応 #1269859

反応方程式

propargyl alcohol

tributyltin hydride

1,1′-azobis(cyclohexanecarbonitrile)

→

desired compound

(E)-3-tributylstannanyl-prop-2-en-1-ol

反応条件

後処理

1. 1
   温度cooled to RT
2. 2
   その他directly purified by CC (EtOAc/Hept 5:95)

実験手順

To neat propargyl alcohol (1.77 mL) were added tributyltin hydride (10.3 mL) followed by 1,1′-azobis(cyclohexanecarbonitrile) (378 mg). The mixture was heated for 2.5 h at 80° C., cooled to RT and directly purified by CC (EtOAc/Hept 5:95) to afford the desired compound (5.4 g).

出典