反応 #1267
ord-9767918db3564609a907b285260c24dc
反応方程式
ethyl 5-(1-piperazinyl)-benzofuran-2-carboxylate
benzyl chloride
→
ethyl 5-(4-benzyl-1-piperazinyl)benzofuran-2-carboxylate
反応条件
詳細条件
See reaction.notes.procedure_details.
実験手順
A solution of 1 g of ethyl 5-(1-piperazinyl)-benzofuran-2-carboxylate in 50 ml of dichloromethane is treated with 1 g of benzyl chloride and stirred for 2 hours. After customary working up, ethyl 5-(4-benzyl-1-piperazinyl)benzofuran-2-carboxylate, m.p. 219°-222°, is obtained.