反応 #1265375

反応方程式

4-vinylbenzylchloride

morpholine

→

product

収率 86.4%

N-(4-Vinylphenyl)methylmorpholine

収率 86.4%

溶媒

methanol

反応条件

後処理

1. 1
   濃縮The mixture was then concentrated in vacuo
2. 2
   その他the resulting residue was partitioned between 1M hydrochloric acid and water [sic]
3. 3
   洗浄The acidic phase was washed with ether
4. 4
   抽出This aqueous phase was extracted with ether
5. 5
   その他This organic phase was dried
6. 6
   濃縮concentrated in vacuo

実験手順

20 ml (0.14 mol) of 4-vinylbenzylchloride and 25 ml (0.28 mol) of morpholine were refluxed in 150 ml of methanol for 3 h. The mixture was then concentrated in vacuo, and the resulting residue was partitioned between 1M hydrochloric acid and water [sic]. The acidic phase was washed with ether and then made alkaline with 2M sodium hydroxide solution. This aqueous phase was extracted with ether. This organic phase was dried and concentrated in vacuo, resulting in 24.6 g of the product.

出典