反応 #1253203

反応方程式

chlorine

3,4-dimethyl-2-pyrazolin-5-one

→

3,4-dimethyl-4-chloro-2-pyrazolin-5-one

溶媒

1,2-dichloroethane

反応条件

後処理

1. 1
   その他After the reaction
2. 2
   温度the reaction mixture was cooled
3. 3
   ろ過filtered
4. 4
   workup.DISTILLATIONThe solvent was then distilled off
5. 5
   その他The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether

実験手順

A chlorine gas was introduced into a solution of 3,4-dimethyl-2-pyrazolin-5-one in 1,2-dichloroethane, followed by gradual refluxing. After the reaction, the reaction mixture was cooled and filtered. The solvent was then distilled off. The residue in the form of an oil was recrystallized from a 1:1 mixture of benzene and petroleum ether, whereby 3,4-dimethyl-4-chloro-2-pyrazolin-5-one was obtained.

出典