反応 #1244247

反応方程式

propanoyl chloride

4-Phenylazophenol

triethylamine

→

product

収率 72.0%

Propionic acid 4-phenylazo-phenyl ester

収率 72.0%

溶媒

ether

ether

反応条件

後処理

1. 1
   その他reaction
2. 2
   洗浄The reaction mixture was washed with water
3. 3
   workup.ADDITIONdilute acid and brine
4. 4
   乾燥dried with magnesium sulfate
5. 5
   その他The solvent was evaporated

実験手順

4-Phenylazophenol (0.25 g, 1.26 mmoles) was dissolved in ether (5-10 mL) and triethylamine (0.26 mL) was added. Then propanoyl chloride (0.14 g 1.5 mmoles) in ether (1 mL) was added dropwise at room temperature. The mixture was stirred and reaction was rapidly completed. The reaction mixture was washed with water, dilute acid and brine and dried with magnesium sulfate. The solvent was evaporated to give 0.23 g (72%) of product. 1H NMR (CDCl3) δ=1.16 (3H, t, J=7.7), 2.40 (2H, q J=7.7), 7.25 (2H, m), 7.40-7.58 (3H, m), 7.88-8.0 (4H, m) ppm.

出典