反応 #1240

ord-3150c5b19251400f94abae6bc2510c0b

反応方程式

CC(C)(C)[Si](C)(C)Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2
7-(1-adamantyl)-6-tert-butyldimethylsilyloxy-2-bromonaphthalene
OBO
boronic acid
→
CC(C)(C)[Si](C)(C)Oc1cc2ccc(B(O)O)cc2cc1C12CC3CC(CC(C3)C1)C2
7-(1-adamantyl)-6-tert-butyldimethylsilyloxy-2-naphthylboronic acid

反応物

CC(C)(C)[Si](C)(C)Oc1cc2ccc(Br)cc2cc1C12CC3CC(CC(C3)C1)C2
7-(1-adamantyl)-6-tert-butyldimethylsilyloxy-2-bromonaphthalene
OBO
boronic acid

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他were obtained

実験手順

Following the basic procedure of Example 7(e), beginning with 11.9 g (25.4 mmol) of 7-(1-adamantyl)-6-tert-butyldimethylsilyloxy-2-bromonaphthalene, 8.37 g (75%) of the expected boronic acid of melting point 221°-222° C. were obtained.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US05723499uspto-grants-1998_03