反応 #1216

反応方程式

1-tridecen-3-ol

m-chloroperbenzoic acid

benzene

→

1,2-epoxy-3-tridecanol

収率 74.0%

溶媒

hexane

反応条件

後処理

1. 1
   その他A 500-ml flask equipped with a stirrer
2. 2
   その他Solids deposited were separated by filtration
3. 3
   workup.DISTILLATIONthe solvent was distilled off under reduced pressure
4. 4
   その他The resultant residue was purified by column chromatography on silica gel

実験手順

A 500-ml flask equipped with a stirrer was charged with 23.8 g (0.12 mol) of 1-tridecen-3-ol, 25.0 g (0.145 mol) of m-chloroperbenzoic acid and 250 ml of benzene, and the contents were stirred at room temperature for 48 hours. After completion of the reaction, 200 ml of hexane. Solids deposited were separated by filtration, and the solvent was distilled off under reduced pressure. The resultant residue was purified by column chromatography on silica gel, thereby obtaining 19.0 g (yield: 74%) of 1,2-epoxy-3-tridecanol.

出典