反応 #1214

反応方程式

N-methylethanolamine

glycidyl tetradecanate

→

title compound

収率 60.8%

3-[N-(2-hydroxyethyl)-N-methylamino]-2-hydroxy-1-propyl tetradecanate

収率 60.8%

溶媒

ethanol

反応条件

後処理

1. 1
   その他A 100-ml flask equipped with a stirrer
2. 2
   その他The resultant reaction mixture
3. 3
   濃縮was concentrated under reduced pressure
4. 4
   その他the residue was purified by chromatography on silica gel

実験手順

A 100-ml flask equipped with a stirrer and dropping funnel was charged with 6.01 g (80 mmol) of N-methylethanolamine, 50 ml of ethanol and 22.8 g (80 mmol) of glycidyl tetradecanate, and the contents were stirred at 80° C. for 2 hours. The resultant reaction mixture was concentrated under reduced pressure, and the residue was purified by chromatography on silica gel, thereby obtaining 17.5 g (yield: 60.8%) of the title compound (IIe-2).

出典