反応 #1210

反応方程式

diethanolamine

cyclohexadecanolide

→

N,N-bis(2-hydroxyethyl)-16-hydroxyhexadecanamide

収率 82.0%

溶媒

water

反応条件

後処理

1. 1
   その他A 200-ml flask equipped with a stirrer
2. 2
   workup.ADDITIONwas added
3. 3
   workup.ADDITIONwas added
4. 4
   ろ過solids deposited were collected by filtration
5. 5
   その他recrystallized from methanol

実験手順

A 200-ml flask equipped with a stirrer was charged with 16.6 g (158 mmol) of diethanolamine and 20.1 g (79 mmol) of cyclohexadecanolide, to which 0.21 g (3.9 mmol) of sodium methoxide was added. The contents were stirred at 80° C. for 18 hours. After completion of the reaction, water was added, and solids deposited were collected by filtration and recrystallized from methanol, thereby obtaining 23.3 g (yield: 82%) of N,N-bis(2-hydroxyethyl)-16-hydroxyhexadecanamide.

出典