反応 #12070

反応方程式

triethylamine

4-vinylbenzyl chloride

monomethyl malonitrile

DMSO

→

pinkish crystals

収率 64.0%

4-(2,2′-dicyanopropyl) styrene

収率 64.0%

溶媒

water

反応条件

後処理

1. 1
   その他A pink solid precipitated
2. 2
   ろ過was filtered
3. 3
   その他The solid was recrystallized from a mixture of methanol and water

実験手順

A sample (2.53 g) of triethylamine (25 mmol) was added dropwise to a mixture of 4.01 g 4-vinylbenzyl chloride (25 mmol), 2.00 g monomethyl malonitrile (25 mmol), and 15 mL DMSO at room temperature. The mixture was stirred at room temperature for 17 hours then poured into 100 mL water. A pink solid precipitated and was filtered. The solid was recrystallized from a mixture of methanol and water to give 3.141 g (64%) of pinkish crystals.

出典