反応 #11965

反応方程式

compound

(S)-2-(4-(N-Boc-aminomethyl)benzoylamino)-4-(N-Boc-amino)butyric acid

hydrochloric acid dioxane

→

title compound

収率 189.4%

(S)-2-(4-aminomethylbenzoylamino)-4-aminobutyric acid

収率 189.4%

溶媒

methanol

反応条件

後処理

1. 1
   その他After the reaction
2. 2
   その他the solvent was removed by distillation
3. 3
   その他the residue was dried

実験手順

The compound obtained in Example 60-2 (49.7 mg) was dissolved in methanol (0.5 ml) and 4 mol/l hydrochloric acid/dioxane solution (0.5 ml) was added. The mixture was stirred for 1.5 hours at room temperature. After the reaction, the solvent was removed by distillation and the residue was dried using a vacuum pump to obtain the title compound (52.4 mg) as a white solid.

出典