反応 #1186777

ord-bedf340c600048ada65056f26a7f2a43

反応方程式

CC/C=C\C/C=C\C/C=C\C/C=C\CCCCC(=O)O
stearidonic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O
γ-linolenic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
dihomo-γ-linolenic acid
→
CCCCC/C=C\C/C=C\CCCCCCCC(=O)O
Linoleic acid
CCCCCCCC/C=C\CCCCCCCC(=O)O
oleic acid

反応物

CC/C=C\C/C=C\C/C=C\C/C=C\CCCCC(=O)O
stearidonic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O
γ-linolenic acid
—
(n-3)-eicosatetraenoic acid
CCCCC/C=C\C/C=C\C/C=C\CCCCCCC(=O)O
dihomo-γ-linolenic acid

試薬

なし

溶媒

—
PUFA

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    workup.ADDITIONin addition to Δ5-desaturase and Δ6-desaturase

実験手順

A number of enzymes are involved in PUFA biosynthesis in addition to Δ5-desaturase and Δ6-desaturase. For example, elongase (elo) catalyzes the conversion of γ-linolenic acid (GLA) to dihomo-γ-linolenic acid (DGLA) and of stearidonic acid (18:4n-3) to (n-3)-eicosatetraenoic acid (20:4n-3). Linoleic acid (LA, 18:2-Δ9,12 or 18:2n-6) is produced from oleic acid (18:1-Δ9) by a Δ12-desaturase. GLA (18:3-Δ6,9,12) is produced from linoleic acid by a Δ6-desaturase.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08143486B2uspto-grants-2012_03