反応 #11852

反応方程式

4-(2-furyl)-1H-pyrrolo[2,3-d]pyrimidine-2-amine

benzyl isocyanate

→

title compound

収率 19.1%

N-benzyl-N′-(4-(2-furyl)-1H-pyrrolo[2,3-d]pyrimidin-2-yl)urea

収率 19.1%

溶媒

THF

反応条件

後処理

1. 1
   ろ過the resulting solid filtered
2. 2
   洗浄washed with EtOAc

実験手順

A solution of 4-(2-furyl)-1H-pyrrolo[2,3-d]pyrimidine-2-amine (192 mg, 0.96 mmol) in THF (3 mL) was treated with benzyl isocyanate (118 μL, 0.96 mmol), stirred at room temperature for 16 h and the resulting solid filtered and washed with EtOAc to give the title compound (61 mg, 19%) as a yellow solid.

出典