反応 #1185

反応方程式

bromine

N-(4-nitrophenyl)-4-methylbenzenesulphonamide

isobutylmagnesium chloride

triethylamine

→

expected product

N-(4-Hydrazino-3-isobutylphenyl)-4-methylbenzenesulphonamide hydrobromide

溶媒

THF

ether

反応条件

後処理

1. 1
   その他This compound is prepared

実験手順

This compound is prepared according to the procedure described in step A of Preparation 2.18, from 10 g of N-(4-nitrophenyl)-4-methylbenzenesulphonamide in 100 ml of THF and 42.6 ml of a 2M solution of isobutylmagnesium chloride in ether, followed by 4.4 ml of bromine and 23.4 ml of triethylamine. 5.9 g of the expected product are obtained, m.p.=170° C.

出典