反応 #1184

反応方程式

1-fluoro-2-methyl-4-nitrobenzene

hydrazine hydrate

hydrazine hydrate

→

expected product

1-Hydrazino-2-methyl-4-nitrobenzene hydrofluoride

溶媒

2-propanol

反応条件

後処理

1. 1
   温度is heated
2. 2
   温度to reflux for 2 hours
3. 3
   温度refluxing
4. 4
   workup.WAITthe mixture is left overnight
5. 5
   その他The precipitate formed

実験手順

A mixture of 4.6 g of 1-fluoro-2-methyl-4-nitrobenzene and 3 ml of hydrazine hydrate in 45 ml of 2-propanol is heated to reflux for 2 hours. 3 ml of hydrazine hydrate are added, refluxing is continued for 2 hours and the mixture is left overnight with stirring at RT. The precipitate formed is drained. 3.53 g of the expected product are obtained, m.p.=182° C.

出典