反応 #1178394

反応方程式

p-methoxybenzophenone

→

1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene

収率 91.0%

溶媒

THF

反応条件

後処理

1. 1
   温度was refluxed for 20 h
2. 2
   ろ過filtered
3. 3
   その他The filtrates were evaporated
4. 4
   その他the crude product was purified by a silica gel column

実験手順

A suspension of p-methoxybenzophenone (1.06 g, 5.0 mmol), 1.34 equiv of TiCl3/AlCl3 (5.81 g, 6.7 mmol), and 25 equiv of Zn dust (8.01 g, 122.0 mmol) in 100 ml of dry THF was refluxed for 20 h. The reaction mixture was cooled to room temperature and filtered. The filtrates were evaporated and the crude product was purified by a silica gel column using hexane as eluent. 1,2-Bis(4-methoxyphenyl)-1,2-diphenylethene (TPE-OMe) was isolated in 91% yield.

出典