反応 #1178393

反応方程式

methacrylic acid

chloromethyl(2-indanyl)ether

toluene

→

(indane-2-yloxy)methyl methacrylate

収率 90.0%

溶媒

triethylamine

反応条件

後処理

1. 1
   温度cooling with agitation
2. 2
   その他After a usual aqueous work-up, the solvent was removed by distillation
3. 3
   その他to obtain a crude product
4. 4
   その他It was purified by a column chromatography

実験手順

Into a mixture of 103 g of methacrylic acid, 183 g of chloromethyl(2-indanyl)ether, and 1500 g of toluene was added 111 g of triethylamine under ice-cooling with agitation, and then the reaction mixture was agitated at room temperature for 16 hours. After a usual aqueous work-up, the solvent was removed by distillation to obtain a crude product. It was purified by a column chromatography to obtain 209 g of an objective product, (indane-2-yloxy)methyl methacrylate (yield 90%).

出典