反応 #1178388

ord-9b6ecdf8dfcc434aa8562bd50920dea3

反応方程式

OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
mannitol
OC[C@@H](O)[C@H](O)[C@@H](O)CO
xylitol
収率 119.7%

反応物

試薬

なし

反応条件

詳細条件
See reaction.notes.procedure_details.

後処理

  1. 1
    その他the resulting wet granules were dried

実験手順

The procedure of Example 1 was repeated except that 300 mg of mannitol was dissolved in a mixture of 10 mg of water and 10 mg of ethanol, the solution was subjected to wet granulation, and the resulting wet granules were dried and used as the sugar alcohol, not 300 mg of xylitol, to obtain an inventive rapidly disintegrating formulation tablet.

出典

DOI: 10.6084/m9.figshare.5104873.v1特許: US08127516B2uspto-grants-2012_03