反応 #1176868

反応方程式

Chlorine

4-amino-3-cyanotrifluoromethyl-benzene

→

4-amino-3-chloro-5-cyano-trifluoromethyl benzene

溶媒

carbon tetrachloride

反応条件

後処理

1. 1
   その他evaporation of the solvent under reduced pressure

実験手順

Chlorine gas was passed through a stirred solution of 4-amino-3-cyanotrifluoromethyl-benzene (5 g) in carbon tetrachloride (75 ml) until the absence of starting material was confirmed by gas liquid chromatography. Flow of the gas was then stopped and evaporation of the solvent under reduced pressure gave 4-amino-3-chloro-5-cyano-trifluoromethyl benzene as an orange solid (5.5 g).

出典