反応 #1166459

反応方程式

hydrochloric acid

p-toluenesulfonic acid chloride

6-pentyloxyheptanol

water

→

(6-pentyloxyheptyl)-p-toluenesulfonate

収率 82.9%

溶媒

pyridine

pyridine

反応条件

後処理

1. 1
   抽出was extracted with ethyl acetate
2. 2
   洗浄The resultant solution was washed with water
3. 3
   乾燥dried with anhydrous magnesium sulfate

実験手順

A solution of 2.26 g of p-toluenesulfonic acid chloride in 5 ml of pyridine was gradually added dropwise to a cooled solution of 2.04 g of 6-pentyloxyheptanol in 8 ml of pyridine for 7 min. below 5° C. After stirring for 5 hours at room temperature, the reaction mixture was injected into 150 ml of cold water and, after being acidified to pH 3 with 6N-hydrochloric acid, was extracted with ethyl acetate. The resultant solution was washed with water and dried with anhydrous magnesium sulfate, followed by distilling-off of the solvent to obtain 2.98 g of (6-pentyloxyheptyl)-p-toluenesulfonate.

出典