反応 #11643

反応方程式

4-(1-methylpiperidin-3-ylmethoxy)-phenylamine

6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one

→

compound

収率 55.0%

6-Fluoro-3-{[4-(1-methyl-piperidin-3-ylmethoxy)-phenylamino]-methylene}-1,3-dihydro-indol-2-one

収率 55.0%

反応条件

後処理

1. 1
   その他are reacted

実験手順

In a manner similar to that described in Example 231, 4-(1-methylpiperidin-3-ylmethoxy)-phenylamine (590 mg, 1.2 equiv.) and 6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (400 mg, 2.23 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (466 mg, 55%).

出典