反応 #1163347

反応方程式

4-t-butylazo-4-cyanovaleric acid

thionyl chloride

→

4-t-butylazo-4-cyanovaleryl chloride

収率 98.8%

溶媒

benzene

反応条件

後処理

1. 1
   その他Into a 25 ml round bottom flask was weighed
2. 2
   workup.DISSOLUTIONThe acid dissolved
3. 3
   その他protected from the atmosphere by a CaCl2 tube
4. 4
   その他At the end of the starting period the benzene and excess thionyl chloride evaporated under reduced pressure

実験手順

Into a 25 ml round bottom flask was weighed 5 grams (.0237 mole) of 4-t-butylazo-4-cyanovaleric acid and then 15 ml of benzene and 2 ml of thionyl chloride were added. The acid dissolved and the solution was stirred for 4 hours at 25°C ± 2°C (protected from the atmosphere by a CaCl2 tube). At the end of the starting period the benzene and excess thionyl chloride evaporated under reduced pressure leaving 5.35 grams (98.8% yield) of 4-t-butylazo-4-cyanovaleryl chloride.

出典