反応 #1144428

反応方程式

1-(methoxymethyl)-6-phenylthiothymine

→

target compound

収率 28.1%

6-phenylthiothymine

収率 28.1%

溶媒

hydrochloric acid

反応条件

後処理

1. 1
   その他to react for 2 hours at 80° C
2. 2
   濃縮The reaction mixture was concentrated under reduced pressure
3. 3
   その他crystallized from ethanol

実験手順

To 100 ml of concentrated hydrochloric acid, 17.2 g (62 mmole) of 1-(methoxymethyl)-6-phenylthiothymine was added and allowed to react for 2 hours at 80° C. The reaction mixture was concentrated under reduced pressure and crystallized from ethanol to obtain 3.8 g of the target compound (Yield: 26%).

出典