反応 #1135838

反応方程式

1-fluoro-2-nitrobenzene

cyclopropyl amine

→

N-cyclopropyl-2-nitroaniline

収率 96.2%

溶媒

ethanol

反応条件

後処理

1. 1
   濃縮concentrated
2. 2
   その他The residue was purified by biotage column chromatography

実験手順

To a solution of 1-fluoro-2-nitrobenzene (0.50 g, 3.5 mmol) in ethanol was added cyclopropyl amine (0.60 g, 10.5 mmol). The solution was heated to 80° C. overnight and concentrated. The residue was purified by biotage column chromatography to give N-cyclopropyl-2-nitroaniline (0.60 g)

出典