反応 #1135798

反応方程式

1-chloro-2-methyl-3-methoxycarbonylaminobenzene

phosphorus pentachloride

→

1-chloro-3-isocyanato-2-methylbenzene

溶媒

chlorobenzene

反応条件

後処理

1. 1
   温度with heating
2. 2
   温度under reflux for one hour
3. 3
   その他The reaction mixtures
4. 4
   濃縮were concentrated under reduced pressure

実験手順

A mixture of the above-mentioned 1-chloro-2-methyl-3-methoxycarbonylaminobenzene 5.80 g, phosphorus pentachloride 7.53 g and chlorobenzene 50 mL was stirred with heating under reflux for one hour. The reaction mixtures were concentrated under reduced pressure to give 1-chloro-3-isocyanato-2-methylbenzene.

出典