反応 #11347
ord-65102f31262e4021b5784cb373f3c5c1
反応条件
詳細条件
See reaction.notes.procedure_details.
後処理
- 1温度the reaction mixture was heated
- 2温度at reflux
- 3その他to yield a clear solution
- 4温度at reflux
- 5その他the solvent was removed in vacuo and excess HCl and thionyl chloride
- 6その他was chased by evaporation with dichloroethane
実験手順
Thionyl chloride (4 mL) was added to a suspension of the benzothiazole-6-sulfonic acid (0.60 g, 2.79 mmol) in dichloroethane (15 mL) and the reaction mixture was heated at reflux and dimethylformamide (5 mL) was added to the reaction mixture to yield a clear solution. After 1.5 hr. at reflux, the solvent was removed in vacuo and excess HCl and thionyl chloride was chased by evaporation with dichloroethane.