反応 #1121771

反応方程式

3-tert-butyldimethylsilyloxybenzoic acid

thionyl chloride

→

3-tert-Butyldimethylsilyloxybenzoyl chloride

反応条件

後処理

1. 1
   温度was heated
2. 2
   温度at reflux for 90 mins
3. 3
   濃縮The reaction mixture was concentrated under reduced pressure
4. 4
   その他to give an oil
5. 5
   その他yield 5.77 parts of the following structure

実験手順

Into a 100 mL round bottom flask a mixture of 5 parts of 3-tert-butyldimethylsilyloxybenzoic acid and 25 mL of thionyl chloride was heated at reflux for 90 mins. The reaction mixture was concentrated under reduced pressure to give an oil, yield 5.77 parts of the following structure.

出典