反応 #1121753

反応方程式

KCl

(S)-5-methyl-3-nitromethyl-hexanoic acid ethyl ester

KOH

HCl

→

title compound

(S)-5-Methyl-3-nitromethyl-hexanoic acid monopotassium salt

溶媒

H2O

反応条件

後処理

1. 1
   その他the solvent was removed under reduced pressure
2. 2
   その他to give a solid

実験手順

830 mg of (S)-5-methyl-3-nitromethyl-hexanoic acid ethyl ester (VIII, R1=ethyl) were suspended in 0.8 mL of H2O. 900 mg of 50% aqueous KOH were added. After 5 h at 25° C. conversion was complete (determination by HPLC). 4.2 mL of 1M aqueous HCl were added and the solvent was removed under reduced pressure to give a solid consisting of the title compound and KCl.

出典