反応 #1121721

反応方程式

chlorosulfonic acid

3-methoxyphenyl benzoate

→

4-benzoyloxy-2-methoxybenzenesulfonic acid

収率 15.0%

溶媒

dichloromethane

dichloromethane

反応条件

後処理

1. 1
   workup.ADDITIONOnce the addition
2. 2
   workup.WAITthe mixture was left
3. 3
   その他to react for 18 h at room temperature
4. 4
   ろ過The formed precipitate was filtered

実験手順

A solution of 0.47 mL (7.01 mmol) of chlorosulfonic acid in 7 mL of dichloromethane was added drop by drop to a solution of 1.6 g (7.01 mmol) of 3-methoxyphenyl benzoate in 12 mL of dichloromethane at 0° C. Once the addition was completed, the mixture was left to react for 18 h at room temperature. The formed precipitate was filtered, giving 300 mg of 4-benzoyloxy-2-methoxybenzenesulfonic acid. Yield 15%.

出典