反応 #1106682

反応方程式

C-Benzo[1,3]dioxol-2-yl-methylamine

sulfamide

→

title compound

(Benzo[1,3]dioxol-2-ylmethyl)sulfamide

溶媒

dioxane

反応条件

後処理

1. 1
   温度the solution was heated
2. 2
   温度to reflux overnight
3. 3
   濃縮The reaction was concentrated
4. 4
   その他the residue was chromatographed (2% to 10% acetone in dichloromethane)

実験手順

C-Benzo[1,3]dioxol-2-yl-methylamine (2.94 g, 19.4 mmol) and sulfamide (3.74 g, 38.9 mmol) were combined in dry dioxane (50 mL) and the solution was heated to reflux overnight. The reaction was concentrated and the residue was chromatographed (2% to 10% acetone in dichloromethane) to yield the title compound as a white solid.

出典