反応 #1106615

反応方程式

2-hydroxy-1-naphthaldehyde

ethanol

aniline

→

2-hydroxy-1-naphthylmethylidene aniline

反応条件

後処理

1. 1
   温度under heating
2. 2
   workup.WAITUpon being left at rest over night in the refrigerator
3. 3
   その他a crystal was formed
4. 4
   その他the resulting precipitation
5. 5
   ろ過was filtered by Kiriyama funnel
6. 6
   その他Drying under reduced pressure at 25° C. for 24 hours

実験手順

6.88 g (40.0 mmol) of 2-hydroxy-1-naphthaldehyde was dissolved in 10 ml ethanol under heating, and 3.72 g (40.00 mmol) of aniline was added. After stirring under reflux at 70° C. for 1 hour, completion of the reaction was confirmed by TLC. Upon being left at rest over night in the refrigerator, a crystal was formed, and the resulting precipitation was filtered by Kiriyama funnel. Drying under reduced pressure at 25° C. for 24 hours gave 2-hydroxy-1-naphthylmethylidene aniline (hereinafter, also referred to as “HNA”) as a yellow crystal (9.17 g, 93%).

出典