反応 #1106613

反応方程式

2-hydroxy-1-naphthaldehyde

ethanol

o-toluidine

→

2-hydroxy-1-naphthylmethylidene-2-methylaniline

反応条件

後処理

1. 1
   温度under heating
2. 2
   濃縮The solution was concentrated with an evaporator to about 30 ml, whereupon a crystal
3. 3
   その他was formed
4. 4
   ろ過which was filtered by Kiriyama funnel
5. 5
   その他Drying under reduced pressure at 25° C. for 24 hours

実験手順

3.44 g (20.0 mmol) of 2-hydroxy-1-naphthaldehyde was dissolved in 50 ml ethanol under heating, and 2.14 g (20.0 mmol) of o-toluidine was added. After stirring under reflux at 70° C. for 1 hour, completion of the reaction was confirmed by TLC. The solution was concentrated with an evaporator to about 30 ml, whereupon a crystal was formed, which was filtered by Kiriyama funnel. Drying under reduced pressure at 25° C. for 24 hours gave 2-hydroxy-1-naphthylmethylidene-2-methylaniline (hereinafter, also referred to as “HNOT”) as a yellow crystal (4.24 g, 81%).

出典