反応 #11040

反応方程式

2,7-dichloromethyl-3,6-di-t-butylfluorene

LiAlH4

→

2,7-di-methyl-3,6-di-tert-butyl-fluorene

収率 85.0%

溶媒

THF

反応条件

後処理

1. 1
   温度the mixture was refluxed for 4 hours
2. 2
   その他The reaction was quenched with water and NaOH
3. 3
   抽出extracted with ether
4. 4
   その他The ether solution was evaporated under vacuum

実験手順

To a solution of 2,7-dichloromethyl-3,6-di-t-butylfluorene (0.75 g, 2.0 mmol) in THF (15 ml) was added a small portion of LiAlH4 (220 mg, 5.8 mmol) under stirring and the mixture was refluxed for 4 hours. The reaction was quenched with water and NaOH and extracted with ether. The ether solution was evaporated under vacuum to give a white solid of 2,7-di-methyl-3,6-di-tert-butyl-fluorene with a yield of 85%.

出典